Jump to content
DOSBODS
  • Welcome to DOSBODS

     

    DOSBODS is free of any advertising.

    Ads are annoying, and - increasingly - advertising companies limit free speech online. DOSBODS Forums are completely free to use. Please create a free account to be able to access all the features of the DOSBODS community. It only takes 20 seconds!

     

How Covid Kills


NTB
 Share

Recommended Posts

I came across this explanation of how the virus works. No idea if it is accurate, I'm not qualified to judge but I think we have a few on here with the knowledge to give it a yes/no/maybe.  This is probably of academic interest only unless it triggers some insight that helps people who catch it.

 

COVID-19 kills people like this: the Spike binds to ACE2, downregulating ACE2. ACE2 can no longer inactivate bradykinin. Bradykinin promotes intracellular calcium rise and cAMP/cGMP activity, triggering various factors that lead to ROS and prostaglandin production. Superoxide reacts with nitric oxide to make peroxynitrite. Peroxynitrite uncouples nitric oxide synthase so that it produces tons of extra superoxide in a vicious cycle that destroys all available NO. The virus's own proteins down-regulate Nrf2 antioxidant activity. Superoxide, hydrogen peroxide, and hypochlorous acid start building up. Iron is stripped out of heme by hypochlorous acid. Iron, superoxide, and hydrogen peroxide make hydroxyl radicals through the Haber-Weiss and Fenton reactions. Hydroxyl radicals attack various lipids/PUFAs and produce various lipid peroxidation byproducts. Oxidized lipids feed into toll-like receptors and trigger autoantibody production and ferroptosis. The extreme oxidative stress promotes the phosphorylation of various triggers of NF-kB and AP-1, promoting IL-6 and TNF-alpha release, along with numerous other inflammatory cytokines and chemokines. This process continuously summons neutrophils, which blast everything in sight with NETs and degranulation products (superoxide dismutase and myeloperoxidase that make more hydrogen peroxide and hypochlorous acid), and monocytes, which actually get infected by the virus and start the same vicious cycle over. Neutrophilia and sepsis set in, along with pulmonary angioedema, coagulopathy, and ARDS. The endothelial lining of blood vessels and the lining of the alveoli in the lungs are utterly ruined by inflammation, edema, and oxidative stress. In extreme cases, multiple organ failure and catastrophic clotting sets in.

Link to comment
Share on other sites

stokiescum

In layman’s terms it gives most it kills pneumonia that’s what’s killing people flu ironicly gives you pneumonia and Covid spreads the same way has flu kills the same way and mutates just like flu.but don’t call it flu that’s sacralige 

Link to comment
Share on other sites

Join the conversation

You can post now and register later. If you have an account, sign in now to post with your account.

Guest
Reply to this topic...

×   Pasted as rich text.   Paste as plain text instead

  Only 75 emoji are allowed.

×   Your link has been automatically embedded.   Display as a link instead

×   Your previous content has been restored.   Clear editor

×   You cannot paste images directly. Upload or insert images from URL.

 Share

  • Recently Browsing   0 members

    No registered users viewing this page.

×
×
  • Create New...